Resumo O objetivo foi avaliar se o suco das folhas de cactáceas de três espécies do gênero Pereskia promove alterações dos parâmetros fisiológicos de ratos Wistar. O estudo foi dividido na etapa 1 (indução da obesidade com dieta hipercalórica, glutamato monossódico e solução de sacarose) e etapa 2 (utilização do suco das cactáceas). Os dados do peso corporal, Índices de Massa Corporal e de Lee, consumo alimentar, massa dos tecidos adiposos e seus Índices de Gordura Visceral e Epididimal foram comparados pelo Teste de Tukey a 5%. O glutamato monossódico e a sacarose em associação com a dieta hipercalórica não aumentaram os tecidos adiposos. Não houve diferença estatística entre as médias do peso corporal, Índice de Massa Corporal e Índice de Lee, peso hepático e o Índice Hepato-Somático. O suco da Pereskia grandifolia promoveu um menor ganho de peso total como resultado do baixo consumo alimentar. O suco da Pereskia aculeata aumentou a massa do tecido adiposo visceral. Concluiu-se que o suco da Pereskia grandifolia apresentou melhor efeito sobre o ganho de peso. Tais cactáceas são ricas em nutrientes e compostos bioativos que poderão melhorar a qualidade alimentar e prevenir doenças crônicas não transmissíveis.

Abstract The objective was to evaluate whether the juice from the leaves of cacti of three species of the genus Pereskia promotes changes in the physiological parameters of Wistar rats. The study was divided into stage 1 (obesity induction with a hypercaloric diet, monosodium glutamate, and sucrose solution), and stage 2 (use of cactus juice). The data of body weight, Body Mass and Lee Indexes, feed intake, adipose tissue mass, and Visceral and Epididymal Fat Indexes were compared by the Tukey test at 5%. Monosodium glutamate and sucrose in association with the hypercaloric diet did not increase adipose tissues. No statistical difference was found between the means of body weight, Body Mass Index and Lee Index, liver weight, and Hepatosomatic Index. Pereskia grandifolia juice promoted a lower total weight gain due to the low feed intake. Pereskia aculeata juice increased the visceral adipose tissue mass. Thus, the Pereskia grandifolia juice presented a better effect on weight gain. These cacti are rich in nutrients and bioactive compounds that can improve food quality, and prevent chronic non-communicable diseases.

ABSTRACT Lychee fruit has been studied owing to the presence of several bioactive compounds that can contribute to weight loss in obese individuals. However, the anti-obese potential of the fruit has not been explored yet. The aim of this study was to investigate the effect of different parts of lychee in reducing the adipose tissue mass of cafeteria diet-fed rats. Phenolic compounds and scavenging capacities were quantified. The food intake, apparent digestibility, weight of the body and liver, body mass, Lee Index, and the mass of epididymal and visceral adipose tissues were evaluated. The results were estimated by Tukey’s Test at 5% probability. A higher amount of phenolic compounds and scavenging capacity were observed in the peel of lychee as compared to the other parts of the fruit. The hypercaloric diet with lychee flour resulted in a higher apparent digestibility. There was no difference between groups control (C), hypercaloric (H), hypercaloric with lychee flour - 50.00% peel and 50.00% seeds (H2F), and hypercaloric with lychee flour - 33.33% peel, 33.33% pulp and 33.34% seeds (H3F) with respect to body and liver weight, corporal mass, and Lee Index. The hypercaloric diet-fed group exhibited an increase in visceral and epididymal adipose tissue mass, whereas the group fed with hypercaloric diets and flour made from the peel and seed of lychee presented a lower visceral adipose tissue mass. In conclusion, the use of lychee flour was considered viable because it decreased visceral adipose tissue mass in rats.